Yes! Android 5.1 is actually a golden era for San Andreas modding because many older modding tools (like CLEO for Android v1.0.5) were built for Android 4.4–5.1.
: Features remastered, high-resolution graphics specifically built for mobile including lighting enhancements, an enriched color palette and improved character models. gta sa android 5.1
In the mid-2010s, on Android 5.1 (Lollipop) was the ultimate portable playground, pushing mobile hardware to its absolute limit. While high-end PC and console players were looking toward newer titles, mobile gamers were rediscovering Los Santos with a unique set of technical quirks and features exclusive to the Android port. The "Lollipop" Experience: Performance & Visuals gta sa android 5.1